CD4(+) lymphocyte-mediated suppression of cytomegalovirus expression in human astrocytes.
نویسندگان
چکیده
Cytomegalovirus-stimulated CD4(+) lymphocytes from seropositive but not seronegative donors suppressed viral gene expression in primary human astrocytes. This suppressive activity was mediated through soluble factors. These findings suggest that CD4(+) lymphocytes play a role in defense of the brain against cytomegalovirus.
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عنوان ژورنال:
- Clinical and diagnostic laboratory immunology
دوره 7 4 شماره
صفحات -
تاریخ انتشار 2000